It is always in one place in San Diego at the San Diego Convention Center
Aside from Ape it is pretty much the biggest Comic Convention on the west coast. I went in 03 when I was stationed near there and it was alot of fun even if you go for the full 4 days you wouldnt be able to see everything.
As for meeting somewhere I would vote for us to meet at the San Diego Airport it is only a short walk from the convention center and the parking would be alot cheaper and easyer to find.
Then afterward us that are "of age" could hit the gaslamp district for some fun lol